Thermo Fisher Scientific HDAC1 Monoclonal Antibody (OTI2D2), TrueMAB
HDAC1 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI2D2). Western blot, ICC/IF, Flow cytometry에 적합. Human HDAC1에 특이적이며, carrier-free 형태로 제공. 동결건조 상태로 보관 및 사용 전 재구성 필요.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D2 |
| Immunogen | Full length human recombinant protein of human HDAC1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, are key in regulating eukaryotic gene expression.
HDAC1 belongs to the histone deacetylase/acuc/apha family and is part of the histone deacetylase complex.
It interacts with the retinoblastoma tumor-suppressor protein, playing a crucial role in controlling cell proliferation and differentiation.
Together with metastasis-associated protein-2, HDAC1 deacetylates p53 and modulates its effect on cell growth and apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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