Thermo Fisher Scientific PEX19 Monoclonal Antibody (GT533)
PEX19 단백질을 인식하는 Mouse IgG2b 단클론 항체로, Western blot, ICC/IF, Flow cytometry에 사용 가능. 인간 및 랫트 반응성. Protein G 정제, PBS buffer, 무보존제. 세포 내 퍼옥시좀 생합성 연구에 적합.
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Thermo Fisher Scientific PEX19 Monoclonal Antibody (GT533)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
| Flow Cytometry (Flow) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GT533 |
| Immunogen | Recombinant fragment containing amino acids 15–299 of PEX19 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.17 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2538747 |
Product Specific Information
- Recommended positive controls: Jurkat, Raji, K562, THP-1, NCI-H929, PC-12, Rat2
- Predicted reactivity: Mouse (91%), Rat (93%), Bovine (95%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
PEX19 is essential for early peroxisomal biogenesis. It functions as a cytosolic chaperone and import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are required for functional peroxisome assembly.
Defects in this gene are associated with peroxisome biogenesis disorders (PBDs), a group of lethal autosomal recessive diseases characterized by multiple peroxisomal function defects. These disorders include Zellweger syndrome (ZWS), in which cells exhibit impaired import of peroxisomal matrix proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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