Thermo Fisher Scientific ROCK1/ROCK2 Recombinant Rabbit Monoclonal Antibody (HL1632)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:10,000

-

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent

-

Immunocytochemistry (ICC/IF)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

HL1632

Immunogen

Recombinant fragment of human ROCK1 .

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_3093954

Target Information

ROCK1 and ROCK2 are genes that encode for Rho-associated coiled-coil containing protein kinases, also known as ROCKs. These kinases are involved in a variety of cellular processes such as cell migration, adhesion, proliferation, and apoptosis. They are activated by the small GTPase RhoA and phosphorylate downstream targets such as myosin light chain, LIM kinase, and myosin phosphatase. Dysregulation of ROCK1 and ROCK2 has been linked to various diseases including cancer, cardiovascular disease, and neurological disorders.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.