Thermo Fisher Scientific Macro H2A.2 Polyclonal Antibody
Rabbit polyclonal antibody against human Macro H2A.2. Validated for Western blot at 1:1,000 dilution. Recognizes histone variant involved in transcriptional repression and chromatin regulation. Suitable for research use only.
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Applications and Tested Dilution
- Western Blot (WB): 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide corresponding to amino acids 148–169 of human H2AFY2 (Histone Macro H2A.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4 °C short term. For long term storage, store at −20 °C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2900974 |
Target Information
Variant histone H2A that replaces conventional H2A in specific nucleosomes, contributing to transcriptional repression. Nucleosomes compact DNA into chromatin, regulating DNA accessibility for transcription, repair, replication, and chromosomal stability. DNA accessibility is modulated by histone post-translational modifications (histone code) and nucleosome remodeling. Macro H2A.2 may play a role in stable X chromosome inactivation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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