Thermo Fisher Scientific IRF9 Polyclonal Antibody
IRF9 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot, IHC, SPR 등 다양한 응용에 적합. 인간 시료에 반응하며, 액상 형태로 제공. 항바이러스 면역 관련 연구에 유용.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.2–1 µg/mL | View 1 publication |
| Immunohistochemistry (IHC) | 5 µg/mL | - |
| Surface Plasmon Resonance (SPR) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human ISGF3G (aa 41–90) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2608188 |
Product Specific Information
Peptide sequence:
PWKHAGKQDF REDQDAAFFK AWAIFKGKYK EGDTGGPAVW KTRLRCALNK
Sequence homology:
Cow: 100%
Dog: 100%
Guinea Pig: 100%
Horse: 100%
Human: 100%
Mouse: 100%
Rabbit: 100%
Rat: 100%
Zebrafish: 79%
Target Information
IRF9 (ISGF3G) is a transcription factor essential for antiviral immunity. It mediates signaling by type I interferons (IFN-α and IFN-β). Upon IFN binding, TYK2 and JAK1 kinases activate STAT1 and STAT2 through phosphorylation. IRF9 associates with the STAT1:STAT2 dimer to form the ISGF3 complex, which translocates to the nucleus and binds to interferon-stimulated response elements (ISREs) to activate transcription of interferon-stimulated genes, driving antiviral responses. [UniProt]
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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