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Thermo Fisher Scientific Phospho-p130Cas (Tyr249) Polyclonal Antibody
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Thermo Fisher Scientific

Thermo Fisher Scientific Phospho-p130Cas (Tyr249) Polyclonal Antibody

상품 한눈에 보기

p130Cas 단백질의 Tyr249 인산화 부위를 인식하는 rabbit polyclonal antibody입니다. Western blot 및 IHC(P) 실험에 사용 가능하며, 세포 신호전달 및 인산화 연구에 적합합니다. 액상 형태로 제공되며, -20°C에서 보관합니다.

브랜드
Thermo Fisher Scientific
카테고리
Polyclonal Antibodies
판매단위
pk

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마지막 업데이트 2025. 08. 02. 오전 05:48
Thermo Fisher Scientific PA538378 Phospho-p130Cas (Tyr249) Polyclonal Antibody 100 ug pk판매 단위 pk ·
재고 확인 필요
688,900원VAT 포함 757,790원
재고문의·견적요청 옵션은 실시간 상담으로 납기를 확인해 드립니다 · 연구비 카드 결제 가능

Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-p130Cas (Tyr249) Polyclonal Antibody

Applications and Tested Dilutions

Application Tested Dilution
Western Blot (WB) 1:500–1:1,000
Immunohistochemistry (Paraffin) (IHC (P)) 1:50–1:100

Product Specifications

항목 내용
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen A synthetic phosphopeptide derived from human p130Cas around the phosphorylation site of Tyr249 (D-I-YP-D-V)
Conjugate Unconjugated
Form Liquid
Concentration 1 mg/mL
Storage Conditions -20°C
Shipping Conditions Wet ice
RRID AB_2554979

Target Information

The p130Cas (Cas for Crk-associated substrate) is a common cellular target of phosphorylation signaling via v-Crk and v-Src oncoproteins. It has a unique structure containing a Src homology (SH)-3 domain followed by multiple YXXP motifs and a proline-rich region. p130Cas is implicated in various biological processes including:

  • Cell adhesion and migration
  • Growth factor stimulation
  • Cytokine receptor engagement
  • Bacterial infection

Physiological functions include cardiovascular development, actin filament assembly, and Src-induced cell transformation.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.

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