Thermo Fisher Scientific SLC39A5 Polyclonal Antibody
SLC39A5 단백질을 표적하는 Thermo Fisher Scientific의 rabbit polyclonal antibody로, WB 및 IHC에 적합합니다. 인간 반응성을 가지며, 합성 펩타이드 면역원으로 제작되었습니다. 액상 형태, 0.5 mg/mL 농도, -20°C 보관 조건.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (IHC) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human SLC39A5 (aa 38–87) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2607174 |
Product Specific Information
- Peptide sequence: HYLAQLFGLY GENGTLTAGG LARLLHSLGL GRVQGLRLGQ HGPLTGRAAS
- Sequence homology:
- Cow: 86%
- Dog: 86%
- Guinea Pig: 86%
- Horse: 93%
- Human: 100%
- Mouse: 93%
- Rabbit: 93%
- Rat: 93%
Target Information
The zinc transporter ZIP5, also known as SLC39A5, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in growth, development, and differentiation. ZIP5 is closely related to ZIP4 and is found in many of the same tissues, including intestine, pancreas, liver, and kidney. Unlike ZIP4, ZIP5 localizes to the basolateral membrane in kidney cells and its activity is not downregulated by zinc repletion. Recent evidence suggests that ZIP4 and ZIP5 are reciprocally regulated, with translation of ZIP5 mRNA decreasing and ZIP5 protein being rapidly internalized and degraded in response to zinc deficiency.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-42523_SLC39A5_Q6ZMH5-1_Rabbit.svg)
(이미지 파일명: PA5-42523_SLC39A5_Q6ZMH5-1_Rabbit_PDP.jpeg)
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