Thermo Fisher Scientific 5HT2A Receptor Polyclonal Antibody
5HT2A 수용체를 인식하는 토끼 폴리클로날 항체로, 인간·생쥐·랫트 반응성. Western blot 및 ELISA에 사용 가능. KLH 접합 합성 펩타이드(aa 171–270) 면역원 사용. 고순도 Protein A 정제, 액상 형태로 -20°C 보관.
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Thermo Fisher Scientific 5HT2A Receptor Polyclonal Antibody
Applications
- Western Blot (WB): 1:300
- ELISA: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human 5HT2A Receptor (amino acids 171–270) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Serotonin plays a major role in cardiovascular function and gastrointestinal motility. It mediates effects through G protein-coupled receptors known as 5-HT or SR receptors.
SR-2 receptors include SR-2A, SR-2B, and SR-2C subtypes, which activate phospholipase C and release intracellular calcium.
- SR-2A: Involved in tracheal smooth muscle contraction, bronchoconstriction, and aldosterone production; associated with psychiatric disorders such as depression and schizophrenia.
- SR-2B: Expressed in cardiovascular tissues, gut, and brain; implicated in cardiac pathology.
- SR-2C: Mediates effects of atypical antipsychotic drugs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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