Thermo Fisher Scientific GM-CSF (Granulocyte/Macrophage - Colony Stimulating Factor) Monoclonal Antibody (BVD2-21C11)
다양한 종(사람, 원숭이)에서 GM-CSF 단백질 검출용 단일클론 항체. Western blot, IHC, ICC, Flow cytometry, IP, 중화시험에 사용 가능. 단백질 A/G 정제, 보존제 없음, -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Frozen) (IHC (F)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
| Immunoprecipitation (IP) | 0.5–1 µg/500 µg lysate |
| Neutralization (Neu) | Assay-dependent |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Cynomolgus monkey, Human, Rhesus monkey |
| Host / Isotype | Rat / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | BVD2-21C11 |
| Immunogen | Recombinant human GM-CSF protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The GM-CSF gene encodes a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active form exists as a homodimer in the extracellular space. This gene is located in a cluster of related genes at chromosome region 5q31, associated with 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include interleukins 4, 5, and 13. GM-CSF promotes tissue inflammation, and elevated levels have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome. Mice lacking this gene or its receptor develop pulmonary alveolar proteinosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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