Thermo Fisher Scientific MRP4 Polyclonal Antibody
Western blot, IHC, ICC, ELISA에 사용 가능한 MRP4 다클론 항체. Human, Mouse, Rat 반응성. Rabbit IgG 기반의 비결합형 항체로, 친화 크로마토그래피로 정제됨. PBS/glycerol buffer에 보관하며 -20°C에서 안정적.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1067–1325 of human MRP4/ABCC4 (NP_005836.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914373 |
Product Specific Information
Positive test controls include HeLa, HeLa cytoplasm extracts, and 293T.
The target is typically localized in the membrane as a multi-pass membrane protein.
Immunogen sequence:
SQEKVGIVGR TGAGKSSLIS ALFRLSEPEG KIWIDKILTT EIGLHDLRKK MSIIPQEPVL FTGTMRKNLD PFNEHTDEEL WNALQEVQLK ETIEDLPGKM DTELAESGSN FSVGQRQLVC LARAILRKNQ ILIIDEATAN VDPRTDELIQ KKIREKFAHC TVLTIAHRLN TIIDSDKIMV LDSGRLKEYD EPYVLLQNKE SLFYKMVQQL GKAEAAALTE TAKQVYFKRN YPHIGHTDHM VTNTSNGQPS TLTIFETAL
Target Information
The protein encoded by this gene is a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intracellular membranes and are divided into seven subfamilies.
This protein belongs to the MRP (multidrug resistance-associated protein) subfamily involved in multidrug resistance. Although its specific function is not fully determined, it may act as a pump for organic anions, contributing to cellular detoxification.
Alternative splicing results in multiple isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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