Thermo Fisher Scientific Phospho-alpha Adducin (Thr445) Polyclonal Antibody
인간 ADD1 Thr445 인산화 부위에서 유래한 합성 인산화 펩타이드로 제작된 rabbit polyclonal 항체. IHC(P)에서 1:50–1:100 희석으로 사용 가능. 액상 형태, 1 mg/mL 농도, -20°C 보관. 세포골격 단백질 adducin 연구용으로 적합.
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- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human ADD1 around the phosphorylation site of Thr445 (E-K-TP-R-W) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2554859 |
Target Information
Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma).
Adducin is a heterodimeric protein consisting of related subunits produced from distinct genes but sharing similar structure.
Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region.
Alpha- and gamma-adducins are ubiquitously expressed, while beta-adducin is highly expressed in brain and hematopoietic tissues.
Adducin binds with high affinity to Ca(2+)/calmodulin and serves as a substrate for protein kinases A and C.
Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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