Thermo Fisher Scientific Phospho-Ku70 (Ser5) Polyclonal Antibody
Phospho-Ku70 (Ser5) 특이적 폴리클로날 항체로 Western blot 및 IHC에 적합. Rabbit IgG 기반으로 제조되었으며, 인산화된 Ku70 Ser5 부위에 대한 높은 특이성과 민감도를 제공. 연구용으로 DNA 손상 복구 관련 단백질 분석에 활용 가능.
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Thermo Fisher Scientific Phospho-Ku70 (Ser5) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human Ku70 around the phosphorylation site of Ser5 (W-E-SP-Y-Y) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2554858 |
Target Information
XRCC6 is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa.
The complex functions as a single-stranded DNA-dependent ATP-dependent helicase and may be involved in the repair of nonhomologous DNA ends, including double-strand break repair, transposition, and V(D)J recombination.
High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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