Thermo Fisher Scientific CD171 Recombinant Rabbit Monoclonal Antibody (14H7)
CD171(L1CAM) 단백질을 인식하는 재조합 토끼 단일클론 항체로, IHC, Flow Cytometry, ELISA에 사용 가능. 인간 시료 반응성, 높은 특이성과 재현성 제공. 액상 형태로 -20°C 이하 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50–1:200 |
| ELISA | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 14H7 |
| Immunogen | A synthesized peptide derived from Human L1CAM |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.8 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3092543 |
Target Information
L1CAM (CD171) is an axonal glycoprotein belonging to the immunoglobulin supergene family. Its ectodomain, composed of immunoglobulin-like and fibronectin type III domains, is linked via a transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule is essential for nervous system development, including neuronal migration and differentiation. Mutations in the L1CAM gene cause X-linked neurological syndromes collectively known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia, and hydrocephalus). Alternative splicing of a neuron-specific exon is functionally relevant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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