Thermo Fisher Scientific TIAM1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1392-1591 of human TIAM1 (NP_0032442) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TIAM1,uniProtId:Q13009-1,ncbiNodeId:9606,antigenRange:1392-1591,antigenLength:1591,antigenImageFileName:PA5-87749_TIAM1_Q13009-1_Rabbit.svg,antigenImageFileNamePDP:PA5-87749_TIAM1_Q13009-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.51 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804386

Product Specific Information

Immunogen sequence: SILRDKHRRQ LLKTESLPSS QQYVPFGGKR LCALKGARPA MSRAVSAPSK SLGRRRRRLA RNRFTIDSDA VSASSPEKES QQPPGGGDTD RWVEEQFDLA QYEEQDDIKE TDILSDDDEF CESVKGASVD RDLQERLQAT SISQRERGRK TLDSHASRMA QLKKQAALSG INGGLESASE EVIWVRREDF APSRKLNTEI; Positive Samples: B cells, Jurkat, A-431, U-87MG, SW480; Cellular Location: Cell junction, Cell membrane, Cytoplasmic side, Peripheral membrane protein

Target Information

Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA. Required for normal cell adhesion and cell migration.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.