Thermo Fisher Scientific Human c-Raf Synthetic Peptide
휴먼 c-Raf의 N-말단 19개 아미노산 서열에 해당하는 합성 펩타이드입니다. 폴리클로날 항체 PA5-20970과 함께 블로킹 펩타이드로 사용 가능합니다. Raf-1 신호전달 연구용으로 적합하며, 액상 형태로 제공되고 -20°C에서 보관합니다.
- 카탈로그번호
- PEP1084
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to 19 amino acids near the amino terminus of human C-raf.
PEP-1084 can be used as a blocking peptide with polyclonal antibody PA5-20970.
Target Information
Raf-1 (c-Raf) is a MAP kinase kinase kinase (MAP3K) functioning downstream of the Ras family of membrane-associated GTPases. Once activated, Raf-1 phosphorylates and activates the dual specificity protein kinases MEK1 and MEK2, which subsequently activate the serine/threonine kinases ERK1 and ERK2. Activated ERKs regulate gene expression involved in cell division, apoptosis, differentiation, and migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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