Thermo Fisher Scientific CTLA4/CD152 (Negative Regulator of T-Cells) Monoclonal Antibody (L4P2F5.F10)
CTLA4/CD152 단백질을 인식하는 Mouse monoclonal antibody로 T세포 음성 조절 연구에 적합. WB, ICC/IF, Flow Cytometry 등 다양한 응용 가능. Bovine, Cat, Mouse, Rat 반응성. Protein A/G 정제, PBS buffer, 무보존제, 액상 형태.
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Thermo Fisher Scientific CTLA4/CD152 (Negative Regulator of T-Cells) Monoclonal Antibody (L4P2F5.F10)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Cat, Mouse, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | L4P2F5.F10 |
| Immunogen | A synthetic peptide from CTLA4 (exact sequence is proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Does not react with Human.
Target Information
CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor expressed mainly on CD4⁺ T cells.
It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells) but with higher affinity.
In contrast to CD28, which enhances T cell activation, CTLA4 inhibits T cell function and prevents activation.
Intracellular CTLA4 is also found in regulatory T cells and may play an important role in their function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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