Thermo Fisher Scientific JAM-A (CD321) Polyclonal Antibody
Human JAM-A (CD321) 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, ELISA, IP 등에 사용 가능. 보존제가 없는 액상 형태이며, Protein A 및 항원 친화 크로마토그래피로 정제됨. 세포 접착 및 tight junction 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:5,000–1:10,000 |
| Immunoprecipitation (IP) | 0.2–1 µL/mg of lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human JAM-A protein (Met1–Ala242) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787902 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human JAM-A/PAM-1/CD321.
Target Information
CD321 (also known as F11R, JAM-1, JAM-A) is a cell-surface adhesion molecule belonging to the Ig superfamily of receptors.
It is a 32–41 kDa glycoprotein with two extracellular Ig-like domains, a transmembrane region, and a short cytosolic tail.
The protein forms homodimers and associates with other membrane proteins such as integrins.
CD321 is expressed on leukocytes, platelets, erythrocytes, stem cells, epithelial and endothelial cells, and mediates cell-cell contact.
It is closely associated with tight junction components such as ZO-1 and occludin and plays roles in maintaining epithelial and endothelial barriers, hematopoiesis, angiogenesis, and tumor progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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