Thermo Fisher Scientific KCNE2 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:5,000
• Publications: [References not provided]

Product Specifications

Product Specific Information

• PA1-9547 detects KCNE2 in human samples.
• Successfully used in Western blot procedures.
• Detects a 12 kDa protein representing KCNE2.
• Immunogen: purified recombinant full-length KCNE2 corresponding to the chromosome 21 gene (Human).

Target Information

Voltage-gated potassium (Kv) channels are complex ion channels with diverse physiological roles, including:

• Neurotransmitter release
• Heart rate regulation
• Insulin secretion
• Neuronal excitability
• Epithelial electrolyte transport
• Smooth muscle contraction
• Cell volume regulation

The KCNE2 gene encodes a small integral membrane subunit that assembles with the KCNH2 gene product, altering its function. It is expressed in heart and muscle, and mutations are associated with cardiac arrhythmia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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