Thermo Fisher Scientific HNF6 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human HNF6. Recombinant protein control fragment (Product #RP-100744). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:HNF6,uniProtId:Q9UBC0-1,ncbiNodeId:9606,antigenRange:160-297,antigenLength:465,antigenImageFileName:PA5-51938_HNF6_Q9UBC0-1_Rabbit.svg,antigenImageFileNamePDP:PA5-51938_HNF6_Q9UBC0-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2642490

Product Specific Information

Immunogen sequence: SMNNLYTPYH KDVAGMGQSL SPLSSSGLGS IHNSQQGLPH YAHPGAAMPT DKMLTPNGFE AHHPAMLGRH GEQHLTPTSA GMVPINGLPP HHPHAHLNAQ GHGQLLGTAR EPNPSVTGAQ VSNGSNSGQM EEINTKEV

Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.

Target Information

Hepatocyte nuclear factor 6 is a CUT homeobox family protein which is a transcription factor and contains a CUT DNA-binding domain and a homeobox DNA-binding domain. It is an upstream regulator of several genes involved in the pathogenesis of maturity-onset diabetes of the young. HNF6 is a ligand of the FOXM1 transcription factor network. HNF6, along with HNF4, controls gene expression in the liver. The expression levels of HNF6 and HNF4 rise steadily during development and that up- or down regulation of HNF6 and HNF4 expression generate premature or delayed expression of the g6pc gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.