Thermo Fisher Scientific RPL7A Monoclonal Antibody (OTI4D5), TrueMAB
RPL7A 단백질을 인식하는 Mouse 단클론 항체로 Western blot 및 IHC에 적합. Human 및 Mouse 반응성. TrueMAB 형식으로 고순도 친화 크로마토그래피 정제. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4D5 |
| Immunogen | Human recombinant protein fragment (aa 2–266 of human RPL7A) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit, composed of 4 RNA species and approximately 80 distinct proteins.
The RPL7A gene encodes a ribosomal protein that is part of the 60S subunit and belongs to the L7AE family. It interacts with certain nuclear hormone receptors, such as thyroid hormone receptor, inhibiting their DNA binding and transactivation ability.
This gene is located in the surfeit gene cluster and co-transcribed with small nucleolar RNA genes (U24, U36a, U36b, U36c). It can rearrange with the trk proto-oncogene to form the chimeric oncogene trk-2h, encoding an oncoprotein combining the N-terminus of RPL7A and the receptor tyrosine kinase domain of trk.
Multiple processed pseudogenes of RPL7A are dispersed throughout the genome.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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