Thermo Fisher Scientific UMPS Polyclonal Antibody
Thermo Fisher Scientific의 UMPS Polyclonal Antibody는 인간 UMPS 단백질을 인식하는 토끼 유래 IgG 항체입니다. WB, IHC, ICC/IF에 사용 가능하며, 고순도 항원 친화 크로마토그래피로 정제되었습니다. 1 mg/mL 액상 형태로 제공되며, 장기 보관 시 -20°C에서 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 217–466 of Human UMPS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547677 |
Product Specific Information
- Recommended positive controls: HeLa, HCT116
- Predicted reactivity: Mouse (90%), Rat (92%), Chicken (81%), Rhesus Monkey (98%), Bovine (89%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes uridine 5'-monophosphate synthase (UMPS), a bifunctional enzyme catalyzing the final two steps of the de novo pyrimidine biosynthetic pathway.
- N-terminal enzyme (orotate phosphoribosyltransferase): Converts orotic acid to orotidine-5'-monophosphate
- C-terminal enzyme (OMP decarboxylase): Converts orotidine-5'-monophosphate to uridine monophosphate
Defects in this gene cause hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-30203_UMPS_P11172-1_Rabbit.svg, PA5-30203_UMPS_P11172-1_Rabbit_PDP.jpeg)
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