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Thermo Fisher Scientific NRSF/REST Polyclonal Antibody
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NRSF/REST 단백질을 인식하는 Rabbit Polyclonal Antibody로, 인간·마우스·랫트 시료에 반응. Western blot, IHC, ICC, ELISA 등 다양한 응용 가능. 고순도 Protein A 정제, 안정적인 액상 형태로 제공. 연구용으로만 사용.
- 카탈로그번호
- BS-2590R
- 판매단위
- pk
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마지막 업데이트 2025. 08. 05. 오후 06:04
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Thermo Fisher Scientific BS-2590R NRSF/REST Polyclonal Antibody 100 ul pk판매 단위 pk ·
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531,800원VAT 포함 584,980원
Thermo Fisher Scientific · Thermo Fisher Scientific NRSF/REST Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human NRSF, amino acids 401–450 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Transcriptional repressor that binds to neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. It restricts the expression of neuronal genes by associating with corepressors mSin3 and CoREST, which recruit histone deacetylase to REST-regulated promoters. REST mediates repression by recruiting the BHC complex at RE1/NRSE sites, leading to histone deacetylation and demethylation, thereby modifying chromatin structure.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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