Thermo Fisher Scientific IL1F9 Monoclonal Antibody (OTI6E4), TrueMAB
IL1F9 단백질을 인식하는 마우스 단클론 항체로, Western blot과 IHC(P)에서 검증됨. 인간 시료 반응성, 무보존제 리오필라이즈드 형태. 연구용으로 NF-kappa-B 및 MAPK 신호 관련 염증 반응 연구에 적합.
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Applications
- Western Blot (WB): 1:4,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6E4 |
| Immunogen | Full length human recombinant protein of human IL1F9 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve ~1 mg/mL final antibody concentration.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
IL1F9 is a cytokine that binds IL1RL2/IL-36R receptor, activating NF-kappa-B and MAPK signaling pathways.
It is part of the IL-36 signaling system involved in local inflammatory responses in epithelial barriers.
Plays a role in skin inflammation by acting on keratinocytes, dendritic cells, and T-cells.
Induces chemokine expression (CCL3, CCL4, CCL5, CCL2, CCL17, CCL22, CXCL8, CXCL1) and proinflammatory markers (TNF-alpha, S100A7, inducible NOS).
May contribute to airway inflammation and innate immune response to fungal pathogens such as Aspergillus fumigatus.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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