Thermo Fisher Scientific IL-18 Polyclonal Antibody
IL-18 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot, IHC, ICC 등 다양한 응용 가능. E.coli 유래 recombinant IL-18(Y37-D193)을 면역원으로 사용. 항원 친화 크로마토그래피로 정제되었으며, 동결건조 형태로 제공. 연구용 전용 시약.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL | View 4 publications |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–5 µg/mL | – |
| Immunocytochemistry (ICC/IF) | 5 µg/mL | – |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E.coli-derived human IL-18 recombinant protein (Position: Y37–D193) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 4 mg trehalose |
| Contains | No preservative |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2746595 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
The protein encoded by this gene is a proinflammatory cytokine that induces IFN-gamma production in T cells. In combination with IL-12, it inhibits IL-4–dependent IgE and IgG1 production while enhancing IgG2a production in B cells. IL-18 binding protein interacts specifically with this cytokine to negatively regulate its biological activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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