Thermo Fisher Scientific GFAP Polyclonal Antibody
GFAP 단백질을 인지하는 기니피그 폴리클로날 항체로, 인간·마우스·랫트 반응성을 보입니다. Western blot 및 IHC에 사용 가능하며, 신경교세포 마커 연구에 적합합니다. 동결건조 형태로 제공되며 장기 보관 시 -20°C에서 안정적입니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host/Isotype | Guinea pig / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from aa region 250–300 of rat GFAP conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water and centrifuge to remove any insoluble material.
- The peptide is homologous in mouse and rat.
- Specificity: GFAP.
Target Information
GFAP (Glial fibrillary acidic protein) is a class III intermediate filament protein, specifically expressed in astrocytes and certain astroglia of the central nervous system. It is also found in satellite cells of peripheral ganglia and non-myelinating Schwann cells. Neural stem cells strongly express GFAP, making it a useful marker for astrocytic cells. GFAP expression is common in various brain tumors derived from astrocytic cells, and it can also be detected in lens epithelium, Kupffer cells, salivary tumor cells, and erythrocytes. Mutations in GFAP cause Alexander disease, a rare astrocyte disorder. Alternative splicing produces multiple isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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