Thermo Fisher Scientific CD11b/c Monoclonal Antibody (OX-42), PE
Thermo Fisher의 CD11b/c (OX-42) PE 결합 단일클론 항체로, Flow Cytometry에 적합합니다. Rat 시료 반응성이 있으며, 단핵구·대식세포 표지에 사용됩니다. 565/576 nm 형광 특성, Protein G 정제, 4°C 보관 조건을 가집니다.
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Applications
- Flow Cytometry (Flow)
Tested Dilution: 0.1 µg/1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OX-42 |
| Immunogen | Rat Peritoneal Macrophages |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 4–5 mg/mL BSA |
| Contains | 0.02% Sodium Azide |
| Storage Conditions | 4°C, Do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2538901 |
Additional Formats
- Unconjugated (MA5-17506)
- APC (MA5-17507)
- Biotin (MA5-17508)
- FITC (MA5-17509)
- Request custom conjugation
Target Information
Integrins are heterodimeric membrane proteins composed of alpha and beta chains. CD11b mediates adhesive interactions of monocytes, macrophages, and granulocytes, and functions as CR3, the receptor for iC3b. It also binds fibrinogen, factor X, and ICAM1. CD11b is present on macrophages, granulocytes, NK cells, and monocytes, and serves as a microglial marker in nervous tissue. CD11c encodes the integrin alpha X chain, forming a leukocyte-specific integrin (CR4) with beta 2 chain. This complex participates in neutrophil and monocyte adhesion and phagocytosis of complement-coated particles. Mutations in CD11b/c are associated with systemic lupus erythematosus 6.
For Research Use Only.
Not for use in diagnostic procedures or resale without authorization.
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