
Thermo Fisher Scientific B1 Bradykinin Receptor (BDKRB1) Polyclonal Antibody
B1 Bradykinin Receptor(BDKRB1)을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체입니다. Western blot과 동결 조직면 IHC에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 염증 반응 관련 연구용으로 사용되며, 동결 건조 상태로 제공됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | (C)KEAS RTRSG GPKGS K, corresponding to amino acid residues 243–257 of rat B1R with replacement of cysteine 250 (C250) with serine (S), 3rd intracellular loop |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitution:
25 µL, 50 µL, or 0.2 mL of double distilled water (DDW) depending on the sample size.
The antibody ships as a lyophilized powder at room temperature. Upon arrival, store at -20°C.
The reconstituted solution can be stored at 4°C for up to 1 week. For longer storage, aliquot and store at -20°C.
Avoid multiple freeze/thaw cycles. Centrifuge all antibody preparations before use (10,000 × g, 5 min).
Target Information
Bradykinin, a 9 amino acid peptide, is generated under pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy.
Two types of G-protein coupled receptors bind bradykinin and mediate responses to these conditions.
The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury.
Receptor binding increases cytosolic calcium ion concentration, leading to chronic and acute inflammatory responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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