Thermo Fisher Scientific PKC zeta Polyclonal Antibody
PKC zeta 단백질을 인식하는 Rabbit Polyclonal Antibody로 인간 시료에 반응합니다. Western blot에 적합하며 항원 친화 크로마토그래피로 정제되었습니다. 보존제가 없으며 -20°C에서 보관합니다. 세포 성장 및 신호전달 연구에 활용됩니다.
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Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to human PKC zeta |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 100 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10983472 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with endogenous levels of other PKC isoforms.
Target Information
The PKC family of serine/threonine kinases, including PRKCZ (PKC zeta), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity.
PKC alpha, beta I, beta II, and gamma form the conventional family; their activities are Ca²⁺- and phospholipid-dependent. PKC zeta plays a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion, and membrane function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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