Thermo Fisher Scientific REG4 Polyclonal Antibody
인간 REG4 단백질을 인식하는 염소 폴리클로날 항체로, WB 및 IHC(P)에서 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 동종 단백질과의 교차 반응이 낮음. 세포 재생 및 암 관련 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–15 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived recombinant human Reg4 (Asp23–Pro158) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2605633 |
Product Specific Information
- In direct ELISAs, approximately 15% cross-reactivity with recombinant mouse (rm) Reg4, rmReg3A, and recombinant rat (rr) Reg3A is observed.
- Less than 5% cross-reactivity with rrReg2 and less than 1% with recombinant human (rh) Reg1B, rhRegIA, rmReg1, rmReg2, and rmReg3D is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
Reg IV belongs to the regenerating gene family within the C-type lectin superfamily. This family is involved in liver, pancreatic, gastric, and intestinal cell proliferation and differentiation. Reg IV is a 158-amino-acid secretory protein implicated in cell regeneration and/or survival with a growth-stimulating effect on pancreatic beta cells. It is highly expressed in colorectal, gastric, prostate, and other cancers. Reg IV-positive tumor cells display phenotypes including mucus-secreting, enterocyte-like, and undifferentiated types.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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