Thermo Fisher Scientific PTPMT1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human PTPMT1. Recombinant protein control fragment (Product #RP-97310). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PTPMT1,uniProtId:Q8WUK0-1,ncbiNodeId:9606,antigenRange:105-191,antigenLength:201,antigenImageFileName:PA5-60557_PTPMT1_Q8WUK0-1_Rabbit.svg,antigenImageFileNamePDP:PA5-60557_PTPMT1_Q8WUK0-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2646121

Product Specific Information

Immunogen sequence: IPTLDNLQKG VQFALKYQSL GQCVYVHCKA GRSRSATMVA AYLIQVHKWS PEEAVRAIAK IRSYIHIRPG QLDVLKEFHK QITARAT

Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 83%.

Target Information

Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). PGP is an essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle. Has also been shown to display phosphatase activity toward phosphoprotein substrates, specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production. Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues. Probably involved in regulation of insulin secretion in pancreatic beta cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.