Thermo Fisher Scientific TAS2R50 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:300–1:2,000

Immunohistochemistry (IHC)

• Tested Dilution: 1:300–1:2,000

Miscellaneous PubMed (Misc)

• Publications: View 1 publication

Product Specifications

Product Specific Information

• Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
• The peptide shares about 90% identity with TAS2R43, TAS2R31, TAS2R30, TAS2R20.
• Specificity: TAS2R50.

Target Information

TAS2R50 belongs to the large TAS2R receptor family. TAS2Rs are expressed on the surface of taste receptor cells and mediate the perception of bitterness through a G protein-coupled second messenger pathway.
Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content.
The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.
Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.

제품 이미지

(이미지 없음)