Thermo Fisher Scientific IFI6 Polyclonal Antibody
Human IFI6 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot 및 Immunocytochemistry에 적합. 항원 친화 크로마토그래피로 정제되어 고순도 확보. 액상 형태로 제공되며 장기 보관 시 -20°C에서 안정적. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full-length Human IFI6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720587 |
Product Specific Information
This antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
G1P3, also known as Interferon alpha-inducible protein 6 (IFI6) and Interferon-induced protein 6-16, is a 130-amino-acid member of the IFI6 family of proteins. It localizes to the mitochondria and functions as a multi-pass membrane protein induced by IFN-α2β. G1P3 plays a major role in the apoptosis pathway by acting as a cell survival protein that inhibits caspase-3 activity, thereby antagonizing apoptosis. It has been implicated in tumorigenesis and is under investigation as a therapeutic target, as reducing G1P3-mediated antiapoptotic signals may improve treatments for myeloma and other malignancies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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