Thermo Fisher Scientific TRPV4 Polyclonal Antibody
TRPV4 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 IHC에 적합합니다. Rat 시료에 반응하며, 합성 펩타이드를 면역원으로 사용했습니다. 동결건조 형태로 제공되며, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunohistochemistry (IHC) | 1:1,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 100–150 of rat conjugated to blue carrier protein was used as the antigen. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: TRPV4.
Target Information
TRPV4 (Transient Receptor Potential Cation Channel Subfamily V Member 4)
TRPV4 is a cation-selective channel activated in response to systemic osmotic pressure. It functions as a non-selective calcium-permeant cation channel involved in osmotic sensitivity and mechanosensitivity.
TRPV4 belongs to the OSM9-like transient receptor potential channel (OTRPC) subfamily within the TRP superfamily of ion channels.
Mutations in the TRPV4 gene are associated with spondylometaphyseal and metatropic dysplasia, as well as hereditary motor and sensory neuropathy type IIC.
Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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