Thermo Fisher Scientific B2M Polyclonal Antibody, MaxPab
인간 B2M 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot에 적합합니다. 비결합(Unconjugated) 상태의 액상 제품이며, 친화 크로마토그래피로 정제되었습니다. PBS(pH 7.4) 완충액에 보존제가 포함되지 않아 민감한 단백질 분석에 적합합니다.
- 카탈로그번호
- H00000567-D01P
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific B2M Polyclonal Antibody, MaxPab
Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | B2M (NP_004039.1, 1–119 a.a.) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence:
MSRSVALAVL ALLSLSGLEA IQRTPKIQVY SRHPAENGKS NFLNCYVSGF
HPSDIEVDLL KNGERIEKVE HSDLSFSKDW SFYLLYYTEF TPTEKDEYAC
RVNHVTLSQP KIVKWDRDMTarget Information
Beta-2-microglobulin (B2M) is a 12–14 kDa protein that is a subunit of the major histocompatibility complex (MHC) class I.
Human B2M is associated with HLA Class I antigens and expressed on various cell types such as lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial and epithelial cells, but absent on erythrocytes.
It is also found in free form in plasma. The amino acid sequence of B2M is homologous to immunoglobulin constant regions with a predominantly beta-pleated sheet structure.
B2M is involved in antigen processing and presentation, TCR signaling, and downstream signaling in naive CD8+ cells.
The B2M gene is located on chromosome 15, and mutations can lead to hypercatabolic hypoproteinemia.
B2M levels are used as a marker for renal function and as a prognostic marker for HIV infection.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.