Thermo Fisher Scientific TGF beta-2 Polyclonal Antibody
TGF beta-2 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC(P)에서 검증됨. Human, Mouse, Rat에 반응하며, 항원 친화 크로마토그래피로 정제됨. 고순도(>95%)로 PBS/glycerol buffer에 보존되며 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | View 1 publication |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 360–400 of Human TGF beta-2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803006 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
Transforming Growth Factor (TGF) betas mediate numerous cell-to-cell interactions during embryonic development. Three mammalian isoforms—TGF beta 1, 2, and 3—are synthesized as precursor proteins that are cleaved to yield a 112 amino acid polypeptide associated with the latent portion of the molecule.
TGF beta polypeptides are multifunctional, influencing cell proliferation, differentiation, and other cellular functions. Both transformed and non-neoplastic tissues release TGF betas, and most mammalian cells possess specific TGF receptors.
Generally, mesenchymal cells are stimulated by TGF beta, while epithelial or neuroectodermal cells are inhibited. TGF beta 1, 2, and 3 exhibit similar biological activities but differ in receptor binding. TGF beta 2 is produced by many cell types and is abundant in porcine platelets and mammalian bone. Latent TGF beta 2 is the predominant isoform found in body fluids such as amniotic fluid, breast milk, and ocular humors.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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