Thermo Fisher Scientific TRHR Polyclonal Antibody
TRHR 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot 및 Immunocytochemistry에 사용 가능. Lyophilized 형태로 제공되며, 재구성 후 -20°C에 보관. TRH 수용체 연구용으로 적합하며, 신호전달 및 신경조절 관련 연구에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:200–1:400
Immunocytochemistry (ICC/IF)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide CKQKPTEKAANYS, corresponding to amino acid residues 337–349 of rat Thyrotropin-releasing hormone receptor 1 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.75 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2736724 |
Product Specific Information
Product is shipped at room temperature as a lyophilized powder and should be stored at -20°C upon receipt.
Reconstitution: Add 50 µL of deionized water.
Target Information
TRH-R is a 398 amino acid integral membrane protein with six transmembrane domains and belongs to the G-protein coupled receptor 1 family.
It acts as a receptor for the signaling hormone TRH and activates the inositol phospholipid–calcium–protein kinase C transduction pathway upon binding with TRH.
Reports suggest that TRH-R functions as a neurotransmitter and neuro regulator that controls dimerization of the TRH receptor and potentiates hormone-induced receptor trafficking.
It is widely expressed in the thyrotroph cells of the anterior pituitary.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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