Thermo Fisher Scientific MUPP1 Polyclonal Antibody
Rabbit 유래 MUPP1 폴리클로날 항체로, Western blot 및 IHC에 적합합니다. 인간 단백질에 반응하며, 합성 펩타이드(aa 1450-1500)를 항원으로 제작되었습니다. 동결 건조 형태로 제공되며, 연구용으로만 사용 가능합니다.
- 카탈로그번호
- OSM00058W-100UL
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:300–1:2,000
Immunohistochemistry (IHC)
- Tested Dilution: 1:300–1:2,000
Miscellaneous PubMed (Misc)
- Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 1450–1500 of human MUPP1 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: MPDZ.
Target Information
MUPP1 (multi PDZ domain protein 1, MPDZ) was discovered as an interacting partner with the 5-HT2C receptor and was found to co-localize with 5-HT2A or 5-HT2C receptors in all regions of the mouse brain, including the choroid plexus.
MUPP1 contains 13 PDZ domains but no apparent catalytic domain. It is concentrated in tight junctions of polarized epithelial cells and binds to claudin-1 and junctional adhesion molecule (JAM).
MUPP1 may function as a multivalent scaffold protein that recruits various proteins to tight junctions and interacts with claudin-8, possibly playing a role in tight junction barrier function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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