Thermo Fisher Scientific ACSL5 Monoclonal Antibody (CL0275)

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

CL0275

Immunogen

Recombinant protein corresponding to Human ACSL5 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ACSL5,uniProtId:Q9ULC5-1,ncbiNodeId:9606,antigenRange:172-269,antigenLength:683,antigenImageFileName:MA5-24595_ACSL5_Q9ULC5-1_House_mouse.svg,antigenImageFileNamePDP:MA5-24595_ACSL5_Q9ULC5-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2637210

Product Specific Information

Immunogen sequence: VHIVNKADIA MVICDTPQKA LVLIGNVEKG FTPSLKVIIL MDPFDDDLKQ RGEKSGIEIL SLYDAENLGK EHFRKPVPPS PEDLSVICFT SGTTGDPK

Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 55%.

Binds to an epitope located within the peptide sequence MDPFDDDLKQ as determined by overlapping synthetic peptides.

Target Information

The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen, and in trace amounts in normal brain, but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.