Thermo Fisher Scientific RAB41 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human RAB41. Recombinant protein control fragment (Product #RP-92007).

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2646248

Product Specific Information

Immunogen sequence: GKTSIISRFM YNSFGCACQA TVGIDFLSKT MYLEDQIVQL QLWDTAGQER FHSLIPSYIR DSTIAVVVYD ITNINSFKET DKWVEHVRAE RGDDVVIMLL GNKIDLDNKR QVTAEQGEEK SRNLNVMFIE TSAKTGYNVK KVI

Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 73%.

Target Information

Rab 41 (Ras-related protein Rab-41) is a 222 amino acid protein that belongs to the small GTPase superfamily and the Rab family.Members of the Rab familyfunction asregulators ofmembrane trafficking. They cycle between inactive GDP-bound and activated GTP-bound states, which is controlled by GTP hydrolysis-activating proteins (GAPs). Rab 41 can be activated by the GAP protein RN-Tre. Localizing to the Golgi complex, Rab 41 is involved in protein transport and participates in GTP binding. Existing as two alternatively spliced isoforms, the gene that encodes the Rab 41 protein maps to human chromosome Xq13.1. Chromosome X consists of about 153 million base pairs and nearly 1,000 genes. Color blindness, hemophilia, and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently as males carry a single X chromosome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.