Thermo Fisher Scientific Integrin beta 7 Polyclonal Antibody
Rabbit 폴리클로날 항체로 인간 Integrin beta 7 단백질을 인식합니다. 액상 형태로 제공되며, 0.9 mg/mL 농도입니다. 단기 보관은 4°C, 장기 보관은 -20°C에서 수행합니다. 세포 부착 및 염증 반응 연구에 적합합니다.
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Thermo Fisher Scientific Integrin beta 7 Polyclonal Antibody
Product Specifications
| 항목 | 내용 |
|---|---|
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ITGB7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.9 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2790753 |
Product Specific Information
Immunogen sequence:
WCKQLNFTAS GEAEARRCAR REELLARGCP LEELEEPRGQ QEVLQDQPLS QGARGEGATQ LAPQRVRVTL RPGEPQQLQV RFLRAEGYPV DL
Target Information
Integrin beta 7 associates with integrin alpha 4 (CD49d) to form the alpha 4 beta 7 integrin LPAM-1, expressed on intraepithelial lymphocytes.
It also associates with alpha E (CD103) to form the alpha E beta 7 integrin HML-1, expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes.
Ligands for LPAM-1 include VCAM-1 (CD106), MAdCAM-1, and fibronectin, while the ligand of HML-1 is E-cadherin (CD324).
Integrin beta 7 plays an important role in the adhesion of leukocytes to endothelial cells, promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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