Thermo Fisher Scientific PLS3 Monoclonal Antibody (C4)
PLS3 단백질을 인식하는 Thermo Fisher Scientific의 C4 단클론 항체. Western blot, IHC(P), ICC/IF에 사용 가능. 인간, 돼지, 쥐 반응성. 단백질 A/G 정제, 1 mg/mL 농도. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–20 µg/mL |
| Immunocytochemistry (ICC/IF) | 5–20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Pig, Rat |
| Host/Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C4 |
| Immunogen | Recombinant Human PLS3 protein, Ala379–Val630 (Accession #P13797) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.05% Proclin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3093361 |
Target Information
Phospholipid scramblases (PLS) translocate phospholipids bidirectionally between the inner and outer leaflets of the plasma membrane and are implicated in apoptosis. Members of this family, PLS1 and PLS3, are both substrates of Protein kinase C (PKC) delta and are phosphorylated by PKC-delta during apoptosis. PKC-delta translocates to mitochondria during apoptosis and phosphorylates PLS3. Overexpression of PLS3 in HEK293 cells enhances apoptosis induced by UV-irradiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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