Thermo Fisher Scientific ERP44 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.2–1 µg/mL

Product Specifications

Product Specific Information

• Immunogen sequence: LHREFHHGPD PTDTAPGEQA QDVASSPPES SFQKLAPSEY RYTLLRDRDE
• Storage guidance: For short term use, store at 2–8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted homology:
  Cow: 93%; Dog: 86%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 79%

Target Information

ERP44 mediates thiol-dependent retention in the early secretory pathway by forming mixed disulfides with substrate proteins through its conserved CRFS motif. It inhibits the calcium channel activity of ITPR1 and may play a role in oxidative protein folding within the endoplasmic reticulum. ERP44 is also required for retaining ERO1L and ERO1LB in the endoplasmic reticulum.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.