
Thermo Fisher Scientific FGD5 Polyclonal Antibody
FGD5 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 ELISA에 적합합니다. 고순도 Affinity Chromatography 정제, 액상 형태, -20°C 보관. VEGF 관련 세포 신호 및 세포골격 연구에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1000–1200 of human FGD5 (NP_6897493) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.13 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806007 |
Product Specific Information
Immunogen sequence:
YLGLLSENCL HSPRLAAAVR EFEQSVQGGS QTAKHRLLRV VQRLFQYQVL LTDYLNNLCP DSAEYDNTQG ALSLISKVTD RANDSMEQGE NLQKLVHIEH SVRGQGDLLQ PGREFLKEGT LMKVTGKNRR PRHLFLMNDV LLYTYPQKDG KYRLKNTLAV ANMKVSRPVM EKVPYALKIE TSESCLMLSA SSCAERDEWY G
Positive Samples: Mouse brain
Cellular Location: Cell projection, Cytoplasm, Early endosome, Endoplasmic reticulum, Golgi apparatus, Cytoskeleton, Ruffle membrane
Target Information
FGD5 activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. It mediates VEGF-induced CDC42 activation and may regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement, and proliferation. It also plays a role in regulating the actin cytoskeleton and cell shape.
주의사항
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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