Thermo Fisher Scientific LRRK2 Polyclonal Antibody
LRRK2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC, Flow cytometry 등 다양한 응용 가능. 항원 친화 크로마토그래피로 정제된 고품질 항체로 파킨슨병 관련 연구에 적합.
- 카탈로그번호
- PA116770
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific LRRK2 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | Assay-Dependent |
| Immunocytochemistry (ICC/IF) | 2–5 µg/mL |
| Flow Cytometry (Flow) | 2.5 µg/mL |
| Immunoprecipitation (IP) | 1:10–1:500 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Bovine, C. elegans, Human, Mouse, Plant |
| Published Species | Fruit fly |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the C-terminal residues 2500–2527 of human LRRK2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at −20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_568606 |
Product Specific Information
The target sequence has 87% sequence homology with rat.
Target Information
LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain. Mutations in LRRK2 have been associated with Parkinson’s disease. LRRK2 belongs to the leucine-rich repeat kinase family and encodes a protein with an ankyrin repeat region, LRR domain, kinase domain, DFG-like motif, RAS domain, GTPase domain, MLK-like domain, and WD40 domain. The protein is mainly cytoplasmic but also associates with the mitochondrial outer membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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