Thermo Fisher Scientific Aurora A Kinase Monoclonal Antibody (ZY191)
Aurora A kinase 단백질을 인식하는 mouse monoclonal antibody (Clone ZY191). Western blot 및 IHC(P) 검증 완료. Human 및 Mouse 반응성. Protein A로 정제된 0.5 mg/mL 액상 항체로, 단기 4°C, 장기 -20°C 보관 권장. 연구용 전용 시약.
- 카탈로그번호
- 604-080
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Aurora A Kinase Monoclonal Antibody (ZY191)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ZY191 |
| Immunogen | Recombinant full-length human Aurora A kinase protein (amino acids 1–403) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C for short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Breast carcinoma
- Cellular location: Nucleus
Target Information
AURKA (Aurora A) is a serine/threonine kinase that regulates mitosis by association with centrosomes. Overexpression of AURKA is observed in many types of cancer. Aurora A plays a key role in cell cycle regulation during anaphase and telophase, particularly in the centrosome/spindle pole region during chromosome segregation.
It is overexpressed in various human cancers including breast, ovarian, and colorectal cancers, and is considered a potential target for anticancer drug development.
Tissue specificity: Highly expressed in testis, weakly in skeletal muscle, thymus, and spleen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.