Thermo Fisher Scientific PTPRN2 Polyclonal Antibody
Human PTPRN2 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF에 적합합니다. 0.2 mg/mL 농도의 액상 제품이며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용되며, 인슐린 의존성 당뇨병 관련 연구에 활용 가능합니다.
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Thermo Fisher Scientific PTPRN2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PTPRN2. Recombinant protein control fragment (Product #RP-88692). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646133 |
Product Specific Information
Immunogen sequence:
QDDDDRLYQE VHRLSATLGG LLQDHGSRLL PGALPFARPL DMERKKSEHP ESSLSSEEET AGVENVKSQT YSKDLLGQQP HSEPGAAAFG ELQNQMPGPS KEEQSLPAGA Q
Highest antigen sequence identity to orthologs:
- Mouse: 50%
- Rat: 54%
Target Information
The protein encoded by this gene belongs to the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate various cellular processes such as cell growth, differentiation, mitotic cycle, and oncogenic transformation.
This PTP has an extracellular region, a single transmembrane region, and an intracellular catalytic domain, representing a receptor-type PTP. The catalytic domain is closely related to PTPRN/IA-2β. Both PTPRN2 and PTPRN are major autoantigens associated with insulin-dependent diabetes mellitus.
Three alternatively spliced transcript variants encoding distinct proteins have been reported.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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