Thermo Fisher Scientific DDX52 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human DDX52. Recombinant protein control fragment (Product #RP-93272). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DDX52,uniProtId:Q9Y2R4-1,ncbiNodeId:9606,antigenRange:15-99,antigenLength:599,antigenImageFileName:PA5-63257_DDX52_Q9Y2R4-1_Rabbit.svg,antigenImageFileNamePDP:PA5-63257_DDX52_Q9Y2R4-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2640481

Product Specific Information

Immunogen sequence: KFDTRRFSAD AARFQIGKRK YDFDSSEVLQ GLDFFGNKKS VPGVCGASQT HQKPQNGEKK EESLTERKRE QSKKKRKTMT SEIAS

Highest antigen sequence identity to the following orthologs: Mouse - 65%, Rat - 60%.

Target Information

The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.