Thermo Fisher Scientific GABRG1 Polyclonal Antibody
GABRG1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunocytochemistry에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, 친화 크로마토그래피로 정제되었습니다. 액상 형태로 -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GABRG1 (Accession Q8N1C3), corresponding to amino acid residues S18–L68. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899900 |
Product Specific Information
Antibody detects endogenous levels of total GABRG1.
Target Information
Gabrg1 encodes a protein that belongs to the ligand-gated ionic channel family. It is an integral membrane protein involved in inhibiting neurotransmission by binding to the benzodiazepine receptor and opening an integral chloride channel. The Gabrg1 gene is clustered with three other family members on chromosome 4.
GABAA receptors are members of the Cys-loop family of ligand-gated ion channels and, along with GABAB receptors, mediate the inhibitory effects of GABA. Structurally, Gabrg1 proteins are pentameric, consisting of five subunits from different families.
Diseases associated with GABRG1 include Alcohol Dependence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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