Thermo Fisher Scientific TOM70 Polyclonal Antibody
TOM70 단백질을 검출하기 위한 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(Paraffin) 실험에 적합하며, 인간·마우스·랫트 반응성. 고순도 친화 크로마토그래피 정제, 액상 형태로 안정적 보관 가능.
- 카탈로그번호
- PA599985
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TOMM70 (Accession O94826), corresponding to amino acid residues A571–L608 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818918 |
Product Specific Information
This antibody detects endogenous levels of total TOM70.
Target Information
Functional mitochondria require up to 1000 proteins to function properly, with 99% synthesized as precursors in the cytoplasm and transported into the mitochondria with the aid of cytosolic chaperones and mitochondrial translocators (import components).
Proteins to be imported are chaperoned to the mitochondria by cytosolic heat shock protein (cHSP70) and are immediately pursued by Translocators of the Outer Membrane (TOMs), followed by transient interactions of the unfolded proteins with Translocators of the Inner Membrane (TIMs).
TOMM70A is ubiquitously expressed in human tissues and localizes in the mitochondria. It may play a significant role in the import of nuclear-encoded mitochondrial proteins with internal targeting sites such as ADP/ATP carriers and uncoupling proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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