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Thermo Fisher Scientific BMI1 Polyclonal Antibody
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BMI1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, IP 등 다양한 응용에 사용 가능. Human 및 Mouse에 반응하며, 항원 친화 크로마토그래피로 정제됨. 액상 형태로 제공되며 4°C에서 보관. 연구용 전용 제품.
- 판매단위
- pk
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마지막 업데이트 2025. 08. 04. 오후 01:43
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Thermo Fisher Scientific A301694A BMI1 Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
658,900원VAT 포함 724,790원
Thermo Fisher Scientific · Thermo Fisher Scientific BMI1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 276 and 326 of human B lymphoma Mo-MLV insertion region 1 homolog (BMI1, UniProt ID: P35226-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Chicken, Bovine, Cat, and Orangutan
Target Information
BMI1 is a component of the Polycomb group (PcG) multiprotein PRC1 complex, which maintains the transcriptionally repressive state of many genes, including Hox genes, throughout development.
The PRC1 complex acts via chromatin remodeling and histone modification, mediating monoubiquitination of histone H2A (Lys-119), resulting in heritable changes in gene expression.
Within the PRC1 complex, BMI1 is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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